It’s been a while, and whoah! have we been drowning in work or what? The media here in Denmark have caught on both our stories about teenage brains and stem cells in mother’s brains.
Here is a nice demo of how MRI can be used to study not only the brain per se, but also how mental functions work as different functional and physical networks. In a really neat study Takanashi et al. in NeuroImage combined fMRI and Diffusion Tensor Imaging, a scanning technique that basically makes it possible to calculate the brain fibers in the brain, i.e. their homogeneity, direction and so forth.
Takanashi et al write:
By combining fMRI and DTI, we show that memory-related areas in the left dorsolateral prefrontal cortex and the left ventrolateral prefrontal cortex each connect with memory-related areas in the left temporal cortex. This result suggests there are two pathways between prefrontal cortex and temporal cortex related to the human memory system.
here are some neat images to tease you to read the article:



Basically, it is interesting to see how our understanding of the brain (and mind) now beins to rely increasingly more on multmodal approaches. Of course, while these methods “only” are MRI methods, other combinations with EEG, PET, MEG and so forth definitely provide novel ways to study the brain/mind connections.
-Thomas
i wonder if DTI will one day be sophisticated enough to track the movements of the water down the axons in a way from which we could deduce the impulse traffic and directions, off course. and if the time resolution could be achieved that could identify all the firing exchanges between different structures invloved in some function, that would really revolutionize brain imaging and understanding of the brain function dynamics.
Hi Ivan,
News to you, then — I blogged about this interesting story a while ago:
http://brainethics.wordpress.com/2006/05/23/an-fmri-revolution/
Basically, it’s a method to measure activity-dependent water movements. It might suffer the same artefact problems as you see in traditional BOLD fMRI, such as susceptibility artefacts, but it might have a better known validity — i.e. we know better what we’re measuring. But the method still needs improvements — and to be implemented at the labs, including our own.
best,
Thomas
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